Salivary melatonin

Melatonin is a hormone primarily produced by the pineal gland, with its synthesis and release largely regulated by the light-dark cycle. It plays a crucial role in managing the body's circadian rhythms, including the sleep-wake cycle. Salivary melatonin levels reflect the circulating concentrations of this hormone, offering a non-invasive method to assess its production. Measurements are typically taken at multiple points throughout a 24-hour period to observe the natural rhythm of melatonin secretion, which usually peaks during the night.