Ceruloplasmin

Ceruloplasmin is a metalloenzyme primarily synthesized in the liver, playing a crucial role in copper metabolism. It transports approximately 90% of the copper in the blood and acts as a ferroxidase, converting ferrous iron to ferric iron, which is necessary for its incorporation into transferrin. This function is vital for proper iron transport and utilization throughout the body, contributing to overall metabolic balance and antioxidant defense. Ceruloplasmin levels can be influenced by various physiological states and underlying conditions, reflecting its multifaceted roles.