Liver

Direct bilirubin

Conjugated fraction — flags cholestasis.

Direct bilirubin, also known as conjugated bilirubin, is a yellow pigment primarily formed in the liver. It results from the liver's processing of unconjugated bilirubin, making it water-soluble and ready for excretion. This process is crucial for removing waste products from the body. Once conjugated, direct bilirubin is released into the bile and subsequently eliminated through the digestive system. Its measurement is an indicator of the liver's ability to process and excrete bilirubin efficiently, providing insight into hepatic and biliary function.