Apolipoprotein E (ApoE) is a lipid-binding protein that plays a crucial role in lipid metabolism, transporting lipids and fat-soluble vitamins through the lymphatic and circulatory systems. The ApoE gene, located on chromosome 17, has three common alleles: ApoE2, ApoE3, and ApoE4. These alleles combine to form six distinct genotypes (E2/E2, E2/E3, E2/E4, E3/E3, E3/E4, E4/E4), each associated with varying efficiencies in lipid transport and associated health implications. Understanding your ApoE genotype can offer insights into your genetic predisposition.
ApoE genotype
Alzheimer's and lipid-risk genotype.