The anti-transglutaminase (tTG) IgG test detects antibodies produced by the immune system in response to tissue transglutaminase. Tissue transglutaminase is an enzyme found in various tissues, including the small intestine. In certain autoimmune conditions, the immune system mistakenly targets this enzyme. The presence of these specific antibodies can indicate an immune response involving the gut, and is often assessed in the context of digestive health.
Anti-tTG IgG
Celiac screen when IgA deficient.