Alanine aminotransferase (ALT), also known as serum glutamic-pyruvic transaminase (SGPT), is an enzyme predominantly found in the liver. It plays a crucial role in amino acid metabolism, converting alanine to pyruvate and alpha-ketoglutarate, which are then used for energy production. When liver cells are damaged, ALT leaks into the bloodstream, making it a valuable indicator of liver health. Higher levels often suggest inflammation or injury to the hepatocytes, the main cells of the liver.
ALT
The most liver-specific enzyme.